Smile! Protein and peptide sample preparation automated

Dedicated instrumentation to improve sample throughput for LC-MS analysis - compatible with all the iST workflows

The challenge:

How do you bring further standardization, reproducibility and hands on time savings to proteomics sample preparation for  LC-MS analysis when you have already successfully addressed  the many challenges of time, sample contamination, sample loss and reproducibility?

The solution:

Automate! Introducing the PreON platform; built to address the demands of reproducible, robust and sensitive proteomics sample preparation for LC-MS analysis. It allows research labs to automate proteomics processing at the push of a button decreasing the hands-on time from 1 hour (iST, iST-NHS and iST-BCT sample preparation) to about 5 minutes!

Apply! Simple, streamline workflows

1. Samples
Samples should be liquid, homogenates or a soft pellet.
2. Lyse, reduce, alkylate
Add LYSE reagent, incubate for 10 mins at 95°C.
3. Digest and label
Cool, add DIGEST reagent, incubate for 60 mins at 37°C. Label according to vendor instructions.
4. Purify
Load onto cartridge, WASH and ELUTE. Dry and resuspend in LOAD.
5. MS analysis
Inject and analyse to see improved peptide identities.

Results

The PreON eliminates manual processing errors and pipetting variability, improving quality and reproducibility. Spend less time preparing your samples, increase throughput and achieve better results.

The PreON significantly reduces variability in chemically-labeled proteomics sample preparation by reducing manual steps and eliminating processing errors. Spend less time preparing your samples while achieving better results.

PreOmics'

PreON

values

Smile

Improved sample quality
  • High reproducibility: R2>0.9
  • Working range: 1-100 µg
  • Increased peptide and protein identifications
  • Can prepare up to 12 unlabeled sample or 16* labeled samples
  • Benchtop footprint (0.81 x 0.65 x 0.62 m HxWxD, weight 71.5kg)
  • Installation and training included

* with sample pooling before clean-up step

Relax

Sample preparation fully automated
  • True walk-away automation for label-free and chemical labeling workflows
  • Eliminates manual processing steps (only 5 mins hands on time)
  • Works seamlessly with pre-loaded PreOmics protocols
  • PreON is installed and running samples in less than a day
  • Intuitive touch screen menus
  • Overnight evaporation option
  • Range of service plans available

Realize

Cleaner peptides ready for analysis
  • Dual clean-up step removes hydrophilic and hydrophobic contaminants
  • Achieve ready to measure peptides
  • Reduce mass spectrometry downtime
  • Optical and ultrasonic detectors for accurate labware and liquid detection
  • Integrated centrifuge (12 position)
  • Onboard heater shaker (10 – 2,000 rpm; up to 83°C)
  • Optional pauses to help maintain TMT efficiency and conserve TMT reagents
  • CE and CSA compliant

Automation for the next generation

PreON

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Instrument
Instrument
Dedicated instrumentation to improve sample throughput for LC-MS analysis - compatible with all the iST workflows
Instrument
Instrument
Dedicated instrumentation to improve sample throughput for LC-MS analysis - compatible with all the iST workflows
Request quote

iST PreON Tips

P.O.00091
1024 tips
 $93 
88 €
Pre-racked, 1024 pcs., 200 µL

iST PreON 8x

P.O.00077
8 sample kit
 $350 
325 €
With PreON plasticware included

iST PreON 96x

P.O.00079
96 sample kit
 $2,840 
2.369 €
With PreON plasticware included

iST-NHS PreON 12x

P.O.00078
12 sample kit
 $530 
480 €
With PreON plasticware included

iST-NHS PreON 96x

P.O.00080
96 sample kit
 $2,840 
2.369 €
With PreON plasticware included

iST-BCT PreON 8x

P.O.00130
8 sample kit
 $407 
385 €
With PreON plasticware included

iST-BCT PreON 96x

P.O.00131
96 sample kit
 $3,550 
3.140 €
With PreON plasticware included
The products displayed are for visual representation only and may differ from those received

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Imagine
Applying the science
Find out more about the wide range of applications and sample types to which PreOmics technology has been successfully applied