Products/PreON

Smile! Protein and peptide sample preparation automated

Dedicated instrumentation to improve sample throughput for LC-MS analysis - compatible with all the iST workflows

The challenge:

How do you bring further standardization, reproducibility and hands on time savings to proteomics sample preparation for LC-MS analysis when you have already successfully addressed the many challenges of time, sample contamination, sample loss and reproducibility?

The solution:

Automate! Introducing the PreON platform; built to address the demands of reproducible, robust and sensitive proteomics sample preparation for LC-MS analysis. It allows research labs to automate proteomics processing at the push of a button decreasing the hands-on time from 1 hour (iST, iST-NHS and iST-BCT sample preparation) to about 5 minutes!

Relax! iST and iST-NHS compatible workflows

1.
Adding samples

Samples should be liquid, homogenates or a soft pellet. Maximum volume 25µL

2.
iST kit set up

Add the appropriate iST, iST-NHS or iST-BCT kit components to PreON

3.
PreON automated sample preparation

Select the appropriate protocol and start

4.
Mass spectrometric analysis

Inject samples into your LC-MS system

5.
Data analysis

Process your data to see improved peptide identities

Specifications

Key features

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Can prepare up to 12 unlabeled sample or 16* labeled samples

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All methods pre-loaded

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Intuitive touch screen menus

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Optional pauses to help maintain TMT efficiency and conserve TMT reagents

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Overnight evaporation option

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User login and run reporting

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Installation and training included

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Range of service plans available

* with sample mixing before clean up step

Technical specifications

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Onboard heater shaker (10 – 2,000 rpm; up to 70°C)

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Integrated centrifuge (12 position, max. 12,000g)

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Single-channel pipette (10 - 200µL)

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Optical and ultrasonic detectors

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Benchtop footprint (0.81 x 0.65 x 0.62 m HxWxD, weight 71.5kg)

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USB port

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Bar-code reader for ease of inputting kits and sample information

Installation requirements

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AC power outlet (100–240 V AC, 50/60 Hz, 650 VA)

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Air temperature 18 to 28°C (64.4 to 82.4°F)

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Relative humidity 15–75% (noncondensing)

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CE and CSA compliant

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For laboratory use only

Results

The PreON eliminates manual processing errors and pipetting variability, improving quality and reproducibility. Spend less time preparing your samples, increase throughput and achieve better results.

The PreON significantly reduces variability in chemically-labeled proteomics sample preparation by reducing manual steps and eliminating processing errors. Spend less time preparing your samples while achieving better results.