Smile! Protein and peptide sample preparation automated

Dedicated instrumentation to improve sample throughput for LC-MS analysis - compatible with all the iST workflows
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The challenge:

How do you bring further standardization, reproducibility and hands on time savings to proteomics sample preparation for  LC-MS analysis when you have already successfully addressed  the many challenges of time, sample contamination, sample loss and reproducibility?

The solution:

Automate! Introducing the PreON® platform; built to address the demands of reproducible, robust and sensitive proteomics sample preparation for LC-MS analysis. It allows research labs to automate proteomics processing at the push of a button decreasing the hands-on time from 1 hour (iST, iST-NHS and iST-BCT sample preparation) to about 5 minutes!

Apply! Simple, streamlined workflows

1. Samples
Samples should be liquid, homogenates or a soft pellet.
2. Lyse, reduce, alkylate
Add LYSE reagent, incubate for 10 mins at high temperature.
3. Digest and label
Cool, add DIGEST reagent, incubate for 60 mins at 37°C. Label according to vendor instructions.
4. Purify
Load onto cartridge, WASH and ELUTE. Dry and resuspend in LOAD.
5. LC-MS analysis
Inject and analyze to see improved peptide identities.

Results

The PreON® eliminates manual processing errors and pipetting variability, improving quality and reproducibility. Spend less time preparing your samples, increase throughput and achieve better results.

The PreON® significantly reduces variability in chemically-labeled proteomics sample preparation by reducing manual steps and eliminating processing errors. Spend less time preparing your samples while achieving better results.

PreOmics®'

PreON®

values

Smile

Improved sample quality
  • High reproducibility: R2>0.9
  • Working range: 1-100 µg
  • Increased peptide and protein identifications
  • Benchtop footprint (0.81 x 0.65 x 0.62 m HxWxD, weight 71.5kg)
  • Installation and training included

Relax

Sample preparation fully automated
  • Can prepare up to 12 unlabeled and 16 labeled samples (standard configuration)
  • 18 labeled samples can now be processed with the new TMTproTM 18-plex upgrade set*
  • True walk-away automation for label-free and chemical labeling workflows
  • Eliminates manual processing steps (only 5 mins hands on time)
  • Works seamlessly with pre-loaded PreOmics® protocols
  • PreON® is installed and running samples in less than a day
  • Intuitive touch screen menus
  • Overnight evaporation option
  • Range of service plans available

*PreON® upgrade set including a purpose-built hardware set and software package. For more information, reach out to your regional sales representative or info@preomics.com.

Realize

Cleaner peptides ready for analysis
  • Dual clean-up step removes hydrophilic and hydrophobic contaminants
  • Achieve ready-to-measure peptides
  • Reduce mass spectrometry downtime
  • Optical and ultrasonic detectors for accurate labware and liquid detection
  • Onboard centrifuge and heater shaker
  • Optional pauses to help maintain TMT efficiency and conserve TMT reagents
  • CE and CSA compliant

Automation for the next generation

PreON®

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Instrument
Instrument
Dedicated instrumentation to improve sample throughput for LC-MS analysis - compatible with all the iST workflows
Instrument
Instrument
Dedicated instrumentation to improve sample throughput for LC-MS analysis - compatible with all the iST workflows
Request quote

iST PreON Tips

P.O.00091
1024 tips
 $118 
111 €
Pre-racked, 1024 pcs., 200 µL

iST PreON 8x

P.O.00077
8-sample kit
 $435 
404 €
With PreON plasticware included

iST PreON 96x

P.O.00079
96-sample kit
 $3,527 
2.942 €
With PreON plasticware included

iST-NHS PreON 12x

P.O.00078
12-sample kit
 $653 
591 €
With PreON plasticware included

iST-NHS PreON 96x

P.O.00080
96-sample kit
 $3,495 
2.915 €
With PreON plasticware included

iST-BCT PreON 8x

P.O.00130
8-sample kit
 $501 
474 €
With PreON plasticware included

iST-BCT PreON 96x

P.O.00131
96-sample kit
 $4,217 
3.730 €
With PreON plasticware included
The PreOmics® products displayed are for visual representation only and may differ from those received

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Applying the science
Find out more about the wide range of applications to which PreOmics technology has been successfully applied