Smile! Protein and peptide sample preparation automated

Dedicated instrumentation to improve sample throughput for LC-MS analysis - compatible with all the iST workflows

The challenge:

How do you bring further standardization, reproducibility and hands on time savings to proteomics sample preparation for  LC-MS analysis when you have already successfully addressed  the many challenges of time, sample contamination, sample loss and reproducibility?

The solution:

Automate! Introducing the PreON platform; built to address the demands of reproducible, robust and sensitive proteomics sample preparation for LC-MS analysis. It allows research labs to automate proteomics processing at the push of a button decreasing the hands-on time from 1 hour (iST, iST-NHS and iST-BCT sample preparation) to about 5 minutes!

Relax! iST and iST-NHS compatible workflows

Adding samples
Samples should be liquid, homogenates or a soft pellet. Maximum volume 25µL
iST kit set up
Add the appropriate iST, iST-NHS or iST-BCT kit components to PreON
PreON automated sample preparation
Select the appropriate protocol and start
Mass spectrometric analysis
Inject samples into your LC-MS system
Data analysis
Process your data to see improved peptide identities


Key features

Can prepare up to 12 unlabeled sample or 16* labeled samples
All methods pre-loaded
Intuitive touch screen menus
Optional pauses to help maintain TMT efficiency and conserve TMT reagents
Overnight evaporation option
User login and run reporting
Installation and training included
Range of service plans available
* with sample mixing before clean up step

Technical specifications

Onboard heater shaker (10 – 2,000 rpm; up to 70°C)
Integrated centrifuge (12 position, max. 12,000g)
Single-channel pipette (10 - 200µL)
Optical and ultrasonic detectors
Benchtop footprint (0.81 x 0.65 x 0.62 m HxWxD, weight 71.5kg)
USB port
Bar-code reader for ease of inputting kits and sample information

Installation requirements

AC power outlet (100–240 V AC, 50/60 Hz, 650 VA)
Air temperature 18 to 28°C (64.4 to 82.4°F)
Relative humidity 15–75% (noncondensing)
CE and CSA compliant
For laboratory use only


The PreON eliminates manual processing errors and pipetting variability, improving quality and reproducibility. Spend less time preparing your samples, increase throughput and achieve better results.
The PreON significantly reduces variability in chemically-labeled proteomics sample preparation by reducing manual steps and eliminating processing errors. Spend less time preparing your samples while achieving better results.
The products displayed are for visual representation only and may differ from those received

PreON instrument and accessories

P.O.00069.   Instrument
iST PreON Tips
1024 tips
85 € | 90 $
Pre-racked, 200 µL
iST PreON 8x
8 sample kit
315 € | 340 $
With PreON plasticware included
iST PreON 96x
96 sample kit
2.300 € | 2.760 $
With PreON plasticware included
iST-NHS PreON 12x
12 sample kit
465 € | 515 $
With PreON plasticware included
iST-NHS PreON 96x
96 sample kit
2.300 € | 2.760 $
With PreON plasticware included

Automation for the next generation

Have a closer look at PreON today!

PreOmics PreON Values


Improved sample quality

High reproducibility: R
Working range: 1-100µg
Increased peptide and protein identifications


Sample preparation fully automated

True walk-away automation for label-free and chemical labeling workflows
Eliminates manual processing steps (only 5 mins hands on time)
Works seamlessly with pre-loaded PreOmics protocols
PreON is installed and running samples in less than a day


Cleaner peptides ready for analysis

Dual clean up step removes hydrophilic & hydrophobic contaminants
Achieve ready-to-measure peptides
Reduce mass spectrometry downtime


Applying the science
Find out more about the wide range of applications and sample
types to which PreOmics technology has been successfully applied