Smile! Protein and peptide sample preparation automated

Dedicated instrumentation to improve sample throughput for LC-MS analysis - compatible with all the iST workflows

The challenge:

How do you bring further standardization, reproducibility and hands on time savings to proteomics sample preparation for  LC-MS analysis when you have already successfully addressed  the many challenges of time, sample contamination, sample loss and reproducibility?

The solution:

Automate! Introducing the PreON platform; built to address the demands of reproducible, robust and sensitive proteomics sample preparation for LC-MS analysis. It allows research labs to automate proteomics processing at the push of a button decreasing the hands-on time from 1 hour (iST, iST-NHS and iST-BCT sample preparation) to about 5 minutes!

Relax! iST and iST-NHS compatible workflows

Adding samples
Samples should be liquid, homogenates or a soft pellet. Maximum volume 25µL
iST kit set up
Add the appropriate iST, iST-NHS or iST-BCT kit components to PreON
PreON automated sample preparation
Select the appropriate protocol and start
Mass spectrometric analysis
Inject samples into your LC-MS system
Data analysis
Process your data to see improved peptide identities


The PreON eliminates manual processing errors and pipetting variability, improving quality and reproducibility. Spend less time preparing your samples, increase throughput and achieve better results.
The PreON significantly reduces variability in chemically-labeled proteomics sample preparation by reducing manual steps and eliminating processing errors. Spend less time preparing your samples while achieving better results.

Automation for the next generation

Have a closer look at PreON today!

PreON Values and Specifications


Improved sample quality

High reproducibility: R
Working range: 1-100µg
Increased peptide and protein identifications
Can prepare up to 12 unlabeled sample or 16* labeled samples
Benchtop footprint (0.81 x 0.65 x 0.62 m HxWxD, weight 71.5kg)
Installation and training included
* with sample pooling before clean up step


Sample preparation fully automated

True walk-away automation for label-free and chemical labeling workflows
Eliminates manual processing steps (only 5 mins hands on time)
Works seamlessly with pre-loaded PreOmics protocols
PreON is installed and running samples in less than a day
Intuitive touch screen menus
Overnight evaporation option
Range of service plans available


Cleaner peptides ready for analysis

Dual clean up step removes hydrophilic & hydrophobic contaminants
Achieve ready-to-measure peptides
Reduce mass spectrometry downtime
Optical and ultrasonic detectors for accurate labware and liquid detection
Integrated centrifuge (12 position)
Onboard heater shaker (10 – 2,000 rpm; up to 83°C)
Optional pauses to help maintain TMT efficiency and conserve TMT reagents
CE and CSA compliant
The products displayed are for visual representation only and may differ from those received

PreON instrument and accessories

P.O.00069.   Instrument
iST PreON Tips
1024 tips
88 €
Pre-racked, 1024 pcs., 200 µL
iST PreON 8x
8 sample kit
325 €
With PreON plasticware included
iST PreON 96x
96 sample kit
2.369 €
With PreON plasticware included
iST-NHS PreON 12x
12 sample kit
480 €
With PreON plasticware included
iST-NHS PreON 96x
96 sample kit
2.369 €
With PreON plasticware included


Applying the science
Find out more about the wide range of applications and sample
types to which PreOmics technology has been successfully applied