Smile! Proteomics sample preparation simplified – even at low-input

The rising demand for affordable, high‑throughput biopharma applications – such as large‑scale cell‑based screening and drug discovery – has accelerated adoption of low‑input proteomics. However, existing workflows struggle to deliver cost‑effective and scalable performance. While advances in MS sensitivity enable robust measurements from limited material, conventional sample preparation methods are not optimized for reliable high‑throughput processing at low inputs. As a result, insufficient peptide recovery remains a critical bottleneck, limiting proteome depth, quantitative accuracy, and data completeness.

Built on proven in‑StageTip (iST) technology, the iST‑S sample preparation kit delivers a cost-effective solution for low‑input, high‑throughput proteomics. It maximizes peptide recovery and proteome depth, enabling meaningful biological insights from limited material. The ready‑to‑use kit supports fast, robust sample preparation in a 96‑well plate format within ~2 hours. Broad compatibility with LC‑MS systems and automation platforms ensures seamless integration into discovery, screening, and profiling workflows at scale.