Smile! Cell lysis and tissue homogenization simplified

Easy to use, fast cell lysis and tissue homogenization for efficient and reproducible sample preparation.
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The challenge:

Reproducible and reliable cell lysis and tissue homogenization needs to produce a smooth and easy to pipette homogenate and minimize the possibility of cross-contamination. A specific consideration for proteomics is the release of the maximum number of proteins to make them accessible for the next steps of sample preparation. Additionally, lab space, the requirement for chiller units, and the noise made by some processes can also impact instrument choice.

The solution:

The BeatBox® is a fast and easy to use instrument for up to 96 samples, which completes the homogenization in as little as 10 minutes without sample cross contamination and minimal heat induction. The BeatBox® has a surprisingly small footprint and quiet operation in comparison to traditional tissue processing machines. With the BeatBox®, cell lysis and tissue homogenization can be integrated into the PreOmics® iST sample preparation workflows.

Apply! Simple, streamlined workflows

1. Preparing samples
Cut tissue into appropriate size or volume of cells
2. BeatBox Tissue Add-on Kit
Add your tissue or cells and the LYSE buffer from iST kit family
3. BeatBox your samples
Select the power and time, then press START
4. Digest and clean-up
Continue with step 2 from selected iST workflow
5. MS analysis
Inject and analyze your samples

Results

BeatBox homogenates show the highest protein yields. ​​Reproducibility of protein yields from different tissues were increased by 2.5x using BeatBox​​

PreOmics®'

BeatBox®

values

Smile

Cell lysis and tissue homogenization simplified
  • Add tissue or cells and lysis buffer; then select your settings in just two clicks for a perfectly homogenized sample
  • Maximum protein release in 10 minutes
  • 1-50 mg of wet tissue or up to 1e7 cells
  • Minimize heat induction and the possibility of cross contamination

Relax

Flexibility and efficiency combined
  • Versatile, it can homogenize multiple tissue and cell types
  • Optimized programs depending on tissue type
  • Flexible throughput; 96 well or 24 single tube format
  • Superior reproducibility

Realize

Next generation technology - today!
  • Small footprint
    >> L 40 x H 26 x W 24 cm - 5kg
    >> L 16" x H 10" x W 10" - 12lbs
  • 7" touch screen simplicity
  • Utilizes PreOmics® Tissue Homogenization kits and GYUTO bead technology
  • Seamlessly compatible with iST workflows for even greater efficiency

Homogenization for the next generation

BeatBox®

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BeatBox®

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Instrument
Instrument
Easy to use, fast cell lysis and tissue homogenization for efficient and reproducible sample preparation.

BeatBox®

Request quote
Instrument
Instrument
Easy to use, fast cell lysis and tissue homogenization for efficient and reproducible sample preparation.
Request quote

BeatBox Tissue Kit 24x

P.O.00128
24-sample kit
 $127 
108 €

BeatBox Tissue Kit 96x

P.O.00121
96-sample kit
 $481 
405 €

BeatBox Bead Remover Foil

P.O.00170
10 pieces
 $150 
130 €
Separations foil for BeatBox bead remover

BeatBox Bead Remover

P.O.00169
Accessory
 $600 
540 €
Removal of all 96 GYUTO beads from the BeatBox Tissue Kit 96x for downstream liquid handling
The PreOmics® products displayed are for visual representation only and may differ from those received

Resources

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Applying the science
Find out more about the wide range of applications to which PreOmics technology has been successfully applied