Bioanalysis and targeted analysis

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Setting the standard for protein and peptide based applications
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Cell lines
SELECT
Model organisms
SELECT
Tissues/FFPE
SELECT
Plants
SELECT
Biological fluids
SELECT
Immunoprecipitations
SELECT
Research and Discovery
SELECT
Bioanalysis and targeted analysis
SELECT

Bioanalysis and targeted analysis

In targeted mass spectrometry-based protein quantification, information about the peptide or protein is already known, typical experiments include:

● Protein dynamics e.g. steady-state concentration, turn-over rates (PK, PD studies)

● Absolute quantitation e.g. biomarker measurement or dosed biological drugs

● Relative quantitation

Consideration of appropriate internal standards in needed, stable-isotope labeled proteins should be added before the digestion step and stable-isotope labeled peptides can be spiked-into our iST, iST-NHS and iST-BCT workflows after the digestion step. Additionally surrogate matrices maybe needed for calibration and quality control samples. Dedicated resources are shown below and our technical support team would be happy to help with advice.


In targeted mass spectrometry-based protein quantification, information about the peptide or protein is already known, typical experiments include:

● Protein dynamics e.g. steady-state concentration, turn-over rates (PK, PD studies)

● Absolute quantitation e.g. biomarker measurement or dosed biological drugs

● Relative quantitation

Consideration of appropriate internal standards in needed, stable-isotope labeled proteins should be added before the digestion step and stable-isotope labeled peptides can be spiked-into our iST, iST-NHS and iST-BCT workflows after the digestion step. Additionally surrogate matrices maybe needed for calibration and quality control samples. Dedicated resources are shown below and our technical support team would be happy to help with advice.


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Applying the science
Find out more about the wide range of applications and sample types to which PreOmics technology has been successfully applied