Publications employing our PreOmics technologies

Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers.

A multifaceted analysis reveals two distinct phases of chloroplast biogenesis during de-etiolation in Arabidopsis.

Mitochondrial morphology, bioenergetics and proteomic responses in fatty acid oxidation disorders.

Hidden information on protein function in censuses of proteome foldedness.

Sulfur sequestration promotes multicellularity during nutrient limitation.

TET2 is a component of the estrogen receptorcomplex and controls 5mC to 5hmC conversionat estrogen receptorcis-regulatory regions.

Deep learning the collisional cross sections of the peptide universe from a million experimental values.

Molecular and metabolomic interventions for identifying potential bioactive molecules to mitigate diseases and their impacts on crop plants.

BAP1 activity regulates PcG occupancy and global chromatin condensation counteracting diffuse PCGF3/5-dependent H2AK119ub1 deposition.

The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA.

Arylsulfonamide mediated RBM39 degradation causes aberrant splicing of mitotic kinesins.

Damage-induced chromatome dynamics link Ubiquitin ligase and proteasome recruitment to histone loss and efficient DNA repair.

Staphylococcus aureus Interferes with Streptococci Spatial Distribution and with Protein Expression of Species within a Polymicrobial Oral Biofilm.

Automated 16-Plex Plasma Proteomics with Real-Time Search and Ion Mobility Mass Spectrometry Enables Large-Scale Profiling in Naked Mole-Rats and Mice.

Urinary proteome profiling for stratifying patients with familial Parkinson’s disease.

Reduced peroxisomal import triggers peroxisomal retrograde signaling.

Advances in quantitative high‐throughput phosphoproteomics with sample multiplexing.

Neural stem cells alter nucleocytoplasmic partitioning and accumulate nuclear polyadenylated transcripts during quiescence.

Uncovering the secretome of mesenchymal stromal cells exposed to healthy, traumatic, and degenerative intervertebral discs: a proteomic analysis.

Crosstalk between Long-Term Sublethal Oxidative Stress and Detrimental Inflammation as Potential Drivers for Age-Related Retinal Degeneration.

ApoC-III is a novel inducer of calcification in human aortic valves.

Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells.

diaPASEF: parallel accumulation–serial fragmentation combined with data-independent acquisition.

Multiplatform Approach for Plasma Proteomics: Complementarity of Olink Proximity Extension Assay Technology to Mass Spectrometry-Based Protein Profiling.

Questioning coverage values determined by 2D Western Blots – a critical study on the characterization of anti‐HCP ELISA reagents.

Evaluation of bovine milk extracellular vesicles for the delivery of locked nucleic acid antisense oligonucleotides.

Cerebral Injury Promotes Regeneration of The Brachial Plexus

Transcriptome assisted label free proteomics of hepatic tissue in response to both dietary restriction and compensatory growth in cattle.

Exosomes for Wound Healing: Purification Optimization and Identification of Bioactive Components.

LSD1 inhibition induces differentiation and cell.

Collagen-rich omentum is a premetastatic.

Metabolic Heterogeneity of Human Hepatocellular Carcinoma (HCC): Implications for Personalized Pharmacological Treatment.

Chromosome separation during Drosophila male meiosis I requires separase-mediated cleavage of the homolog conjunction protein UNO.

Selective Histone Deacetylase 6 Inhibitors Restore Cone Photoreceptor Vision or Outer Segment Morphology in Zebrafish and Mouse Models of Retinal Blindness.

Yeast homologs of human MCUR1 regulate mitochondrial proline metabolism.

Abiotic and past climatic conditions drive protein abundance variation among natural populations of the caddisfly Crunoecia irrorata.

Annexin A1–dependent tethering promotes.

The extracellular matrix composition of the optic nerve subarachnoid space.

The metalloprotinase ADAMTS5 is expressed by interstitital inflammatory cells in IgA nephropathy and is proteolytically active on the kidney matrix.

Extrinsic immune cell-derived, but not intrinsic oligodendroglial factors contribute to oligodendroglial differentiation block in multiple sclerosis.

Generation and validation of recombinant antibodies to study human aminoacyl tRNA synthetases

An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress.

Preclinical Pulmonary Fibrosis (PrePF) Circulating Protein Biomarkers.

Mutations in the exocyst component EXOC2 cause severe defects in human brain development.

Molecular classification of the placebo effect in nausea.

Rescue of oxytocin response and social behaviour in a mouse model of autism.

Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction.

Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona.

Multi-level proteomics reveals host-perturbation strategies of SARS-CoV-2 and SARS-CoV.

The proteome landscape of the kingdoms of life.