Applications/Bioanalysis and targeted analysis

Plan! Use PreOmics' products for your research

Setting the standard for protein and peptide based applications
Research and Discovery
SELECT
Characterization of proteins and biopharmaceuticals
SELECT
Bioanalysis and targeted analysis

Bioanalysis and targeted analysis

In targeted mass spectrometry-based protein quantification, information about the peptide or protein is already known, typical experiments include:
 ·      Protein dynamics e.g. steady-state concentration, turn-over rates (PK, PD studies)
·      Absolute quantitation e.g. biomarker measurement or dosed biological drugs
·      Relative quantitation
Consideration of appropriate internal standards in needed, stable-isotope labelled proteins should be added before the digestion step and stable-isotope labelled peptides can be spiked-into our iST and iST-NHS workflows after the digestion step. Additionally surrogate matrices maybe needed for calibration and quality control samples. Dedicated resources are shown below and our technical support team would be happy to help with advice.

PreOmics Values

Smile

Improved sample quality

High reproducibility: R
2
>0.9
Working range: 1-100 µg
Increased peptide and protein identifications

Relax

Quicker methodology

Less than 2.5 hours hands-on time
Single step incorporating lysis, reduction and alkylation
All-in-one solution, all reagents provided
Compatible with standard lab equipment

Realise

Cleaner peptides ready for analysis

Dual clean up step removes hydrophilic and hydrophobic contaminants
Achieve ready-to-measure peptides
Reduce mass spectrometry downtime
Manual to fully automated processing options available

Imagine

Applying the science
Find out more about the wide range of applications and sample
types to which PreOmics technology has been successfully applied