Applications/Research and Discovery

Plan! Use PreOmics products for your research

Setting the standard for protein and peptide based applications
Research and Discovery
Characterization of proteins and biopharmaceuticals
SELECT
Bioanalysis and targeted analysis
SELECT

Research and Discovery

Research and discovery covers a wide range of experimental designs and investigations including:
      
● Bottom-up proteomics for changes in protein expression e.g. disease versus healthy or dosed versus placebo
● Biological mechanism understanding:
       o  Metabolic pathway elucidation
       o  Protein functionality pathway where one or more genes are silenced in one specific condition and global proteomic analysis is performed to compare silencing sample to a control/wild type sample
       o  Protein interaction studies e.g.protein : protein or protein : drug
       o   Protein localisation e.g. identification of cellular compartment or across a tissue slice tumour or healthy

Our iST kits are suitable for experiments with metabolic labeling or in label-free mode, whereas our iST-NHS kits are suitable for experiments with chemical labeling such as iTRAQ or TMT. Protocols are also available where immunoprecipitation is used for enrichment. Dedicated resources are shown below and our technical support team is would be happy to help with advice.

PreOmics Values

Smile

Improved sample quality

High reproducibility: R
2
>0.9
Working range: 1-100µg
Increased peptide and protein identifications

Relax

Quicker methodology

Less than 2.5 hours hands-on time
Single step incorporating lysis, reduction and alkylation
All-in-one solution, all reagents provided
Compatible with standard lab equipment

Realise

Cleaner peptides ready for analysis

Dual clean up step removes hydrophilic and hydrophobic contaminants
Achieve ready-to-measure peptides
Reduce mass spectrometry downtime
Manual to fully automated processing options available

Imagine

Applying the science
Find out more about the wide range of applications and sample
types to which PreOmics technology has been successfully applied