Products/PreON iST-NHS

Smile! Chemically labelled sample preparation automated

Dedicated instrumentation to improve sample preparation for TMT chemical labelling for LC-MS

The challenge:

Can you integrate efficient chemical labeling with reproducibility and hands on time savings to proteomics sample preparation for  LC-MS analysis? Chemical labeling reagents have practical handling considerations which must be accomodated when automating a workflow.

The solution:

Automate! Introducing the PreON platform with a dedicated chemical labeling protocol which has been designed to allow for pause steps to insert the labeling reagents immediately before the labeling step. The purification step is carried out after labeling to ensure removal of excess label to prevent interfering peaks. It allows research labs to automate proteomics processing at the push of a button decreasing the hands on time from 2 hours (iST-NHS sample preparation) to about 5 minutes!

Apply! iST and iST-NHS compatible workflows

1.
Adding samples
Samples should be liquid, homogenates or a soft pellet.
2.
iST kit set up
Add the appropriate iST or iST-NHS kit components to PreON.
3.
PreON automated sample preparation
Select the appropriate protocol and start.
4.
Mass spectrometric analysis
Inject samples into your LC-MS system.
5.
Data analysis
Process your data to see improved peptide identities.

Results

The PreON significantly reduces variability in chemically-labeled proteomics sample preparation by reducing manual steps and eliminating processing errors.
Spend less time preparing your samples while achieving better results.
The products displayed are for visual representation only and may differ from those received

PreON instrument and chemical labeling accessories

PreON
P.O.00069   Instrument
iST PreON Tips
P.O.00091
1024 tips
85 €
Pre-racked, 200 µL
iST-NHS PreON 12x
P.O.00078
12 sample kit
465 €
With PreON plasticware included
iST-NHS PreON 96x
P.O.00080
96 sample kit
2,300 €
With PreON plasticware included

Automation for the next generation

Have a closer look at PreON today!

PreOmics PreON Values

Smile

Improved sample quality

High reproducibility: R
2
>0.9
Working range: 1-100 µg
Increased peptide and protein identifications

Relax

Sample preparation automated

Fully automated for your chemical labeling workflows
Eliminates manual processing steps ( only 5 mins hands on time)
Works seamlessly with pre-loaded PreOmics protocols
PreOn is installed and running samples in less than a day

Realise

Cleaner peptides ready for analysis

Dual clean up step removes hydrophilic and hydrophobic contaminants
Achieve ready-to-measure labeled peptides
Reduce mass spectrometry downtime

Imagine

Applying the science
Find out more about the wide range of applications and sample
types to which PreOmics technology has been successfully applied